406.

Mamduh S, Lowry DC, Kratzer FH, Norris LC. Effect of NTA and EDTA on calcium metabolism of chickens and Coturnix. J Nutr. 1978; 108(4):719-730. (CA) [Five expts. were conducted in which various levels of nitrilotriacetic acid (NTA) or its salt, Na2NTA, disodium EDTA (Na2EDTA), and Ca were fed to young chicks, young quail, and adult quail. The duration of trials was from 1 to 28 days of age for chicks, 7 to 49 for young quail, and 167 to 210 for adult quail. Feeding 0.71% NTA or an equimolar level of Na2NTA caused a moderate decrease in chick wt., and Na2EDTA caused a drastic decrease in body wt. of chicks and adult quail. Feeding Na2EDTA caused greater mortality in chicks receiving a low-Ca diet than a higher level of Ca. Plasma Ca levels were increased by NTA in young quail and by Na2NTA in adult quail; in contrast, they were decreased by Na2EDTA in adult quail. Dietary NTA promoted greater tibia mineralization (ash/dry matter) in growing chicks. Dietary NTA increased the deposition of Zn and Mn, in chick tibia, but, it decreased Mg. On the other hand, Na2EDTA decreased Zn and Fe in chick tibia and increased Mn. Coturnix were less sensitive than chickens in responding to dietary chelates.]

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