323.

Gilsanz V, Palacios JM, Rico GG. Treatment of chronic lead poisoning with calcium ethylenediaminetetraacetate (Ca EDTA). Rev. Clin. Espafl. 1955; 57:224-229. (CA50:484e) [Intravenous administration of Ca EDTA to the patients was followed by an extremely rapid disappearance of all symptoms except radial nerve palsy, which is slow to disappear or does not respond to treatment. Anemia disappeared after a reticulocyte crisis. Urinary excretion of Pb increased remarkably. In a case of Pb-poisoning colic Ca EDTA gave relief of pain in 90 min. Intravenous doses of 935 mg./day were given to some patients for 22 days without causing toxic manifestations. A patient with radial nerve palsy whose other symptoms of plumbism had been cured was given 2 g. orally for 7 days. This resulted in digestive disturbances, a rise in serum Ca and P, and progressive anemia and leukopenia.]

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