249.

Bautista ZP (Harper Hosp., Detroit, Mich.). Lead poisoning. A review and report of seven cases. Harper Hosp. Bulletin. 1963; 21:43-55 (Mar.-Apr.). (3016) [The literature on Pb poisoning is reviewed on the basis of 53 references and results of a study on 7 children, 1-3 yr old, are reported. All 7 had histories of pica and their poisoning occurred during the summer months. The urinary level of Pb was above the normal of 0.05 mg/100 ml/day in al 7; 3 showed changes of the central nervous system. X-ray studies showed radiopaque densities in the gastrointestinal tract and an increase in metaphysical densities in 5. Basophilic stippling was found in only 2 children, 3 showed microcytic and hypochromic red blood cells. Three had elevated protein. EDTA was administered orally or iv at daily doses of 65 mg/kg for 5 days or in 2 or 3 courses of 5 days each. A 5-day regimen of 75 mg/kg/day of EDTA in 100-200 ml of 5% dextrose in water, administered in 2 equal doses at a 12-hr (rest of text cut off).]

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