120.

Sapeika N. Actions of lead ethylenediaminetetraacetic acid (EDTA) complex. Arch. Intern. Pharmacodynamie. 1955; 101:488-494. (CA49:14168e) The Pb complex of EDTA is a very water sol. and nontoxic radio-opaque substance. In doses of 1 ml./kg. of a 50% soln., it produces in cats, rabbits, and rats hypotension and depression of the myocardium, both transient. Intestine and nonpregnant uterus muscles were not affected, and pregnancy in rats was not disturbed. It is suggested as a possible contact medium for both oral and parenteral use in man.

Gordon Research Institute / Reference Material

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