88.

Reinl W. Prophylaxis of lead workers with orally administered Ca2EDTA. Zentralblatt fur Arbeitsmedizin und Arbeitsschutz. 1956; 6:5-8 (Jan.). (1709) [The oral administration 3 times/day for 6 wk of "Mosatil" tablets containing 1 g Ca2EDTA, to 17 workers in a Pb foundry, exhibiting established porphyrinuria, was effective in controlling it completely in al but 2 cases. In the latter, medication had been interrupted. The Pb content of the blood was also greatly diminished. The control group of 10 workers who received no EDTA also showed a certain improvement, indicating that strict supervision of precautionary measures had a favorable influence. On the basis of this investigation, the oral administration of 1 g Ca2EDTA 3 times/day to Pb workers who exhibit signs of Pb absorption, brings about improvement in the condition and prevents the establishment of Pb poisoning. The effect is seen as a certain elimination of Pb from the blood by way of the urinary system and in the binding of the Pb, ingested in the course of work, into a nonabsorbable compound.

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