7.

Williams JD, Matthews GA, Judd AW. (St. Paul's Hospital) Oral calcium disodium versenate in treatment of lead poisoning. British J Ind Med. 1962; 19-211-215 (July). (2491) [Eight Pb workers, 34-60 yr old, who had been exposed to Pb from 3 mo-12 yr and showed an excessive Pb absorption, were treated orally with 4 g CaNa2EDTA/day in divided doses for 7 days. Before treatment Pb values ranged from 1.0-170 mg/100 ml in blood, 140-940 mg/l in urine; coproporphyrin, 1+-4+, and stippled cells, 1800-56,000/million. Following treatment the total Pb excretion in urine ranged from 7.6-23.8 mg, av 14.32 mg Pb/man. In 7 cases hemoglobin level rose an av of 1.0 g%; stippled cell count was lower in 4 cases and higher in 4. Pb levels in blood fell in 5 patients, remained the same in 1, and rose in 1. No side effects were noticed and symptomatically the improvement was marked.]

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