ABSTRACT
We first published the start of this study in Volume 11 of Explore Magazine on Nov 6th 2002. This is an ongoing report on the 49 patients previously reported plus their total numbers are up to 63 as new patients have started the protocol. The basic premise is that Calcium EDTA Chelation; itself a new innovation has been performed on these patients accompanied by a supplement program using Homotoxicology remedies manufactured by Heel and the results seem to show that more metals are excreted when Homotoxicology is added to the patient protocols. Since the publication numerous questions have been received regarding other chelating agents such as DMPS/DMSA used for direct Mercury Chelation. There was also an article in the Jan23rd 2003 issue of The New England Journal of Medicine with a study that showed CaEDTA Chelation used for Lead Exposure improved Renal Function which is one of the first studies that showed the benefits of this newest chelating agent. Our Update report summarized herein continues to confirm that Homotoxicology optimizes the effects of CaEDTA Chelation

The reader is directed to reread the First Article in the Nov 6th 2002 Issue of Explore, Volume 11, Number 6, in order to understand the rationale for this unique set of procedures.

The Homotoxicology Supplement Protocol included:

1. The Apothecure Chelation Mineral Supplement Capsule PLUS Heel's MOLYBDAN COMPOSITUM to aid its Effect.
2. BHI INFLAMMATION, ENGYSTOL and CALCOHEEL (some have substituted BHI BONE instead) to treat those micro-organisms alleged to lay down a BioSlime layer and infect the lining of the Arteries
3. TONSILLA COMPOSITUM to stimulate the Adrenal Glands
4. The HEEL Detox Kit remedies added to Drinking Water; NUX VOMICA HOMACCORDE, BERBERIS COMPOSITUM and NUX VOMICA HOMACCORDE
5. BHI ENZYME added to the Digestive Enzyme Endozyme from Longevity Plus to stimulate aerobic Metabolism in the Mitochondria
6. If Cholesterol is an issue, BARIJODEEL added to the NUX VOMICA in the Detox Protocol
7. If Angina is an issue, CRALONIN and COR COMPOSITUM added to the protocol
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8. If Diabetes is present, SYZIGIUM COMPOSITUM, AESCULUS COMOPOSITUM and GALIUM COMPOSITUM added to the drinking water of the Detox Kit

THE OTHER SUPPLEMENTS GIVEN TO THE PATIENTS INCLUDED

1. Longevity Plus BEYOND CHELATION VITAMIN Pack once or twice per day
2. Pleo-Muc Protocol using Sanum/Pleo remedies
3. Apothecure Chelation Replacement Minerals
4. 3-6 Grams of Vitamin C per day
5. Longevity Plus Endozyme and FYI
6. Bimonthly Ultra-Violet Irradiation followed by Hydrogen Peroxide IV with a CaEDTA push
7. Colon Reflorastation Biannually
8. Homeopathic and Chiropractic Care as appropriate

THE FORMULA FOR THE 30 MINUTE CHELATION EDTA IV is as follows:

In 100ml NORMAL SALINE, ADD

1.0cc Vitamin B-6 (100 mg/ml)

0.25cc Vitamin B-1 (100mg/ml)

0.25cc Vitamin B complex-100

1.0cc Vitamin B-12 (1000ug/ml)

2.0cc Vitamin B-5 (250mg/ml)

3.0cc Vitamin C (beet derived) 500mg/ml

2.0cc Magnesium Chloride (200mg/ml)

2.5cc Potassium Chloride (2Meq/ml)

0.1cc Heparin (5000USP Units/ml)

10.0cc Calcium DiSodium EDTA (300 mg/ml)

     Adjusted per Cockcroft Gault Formula

It must be pointed out that the Doctors Data scale is different for each metal. A reading of 3 on Mercury is as significant as 100 on Arsenic. The numbers must only be compared to the ones directly above and below each other.

1. ARSENIC peaks at the second collection and drops off by the third
2. CADMIUM stays relatively stable throughout the process
3. LEAD progressively decreases with each progressive set of IVs
4. NICKEL Increases in excretion as each progressive set of IVs goes forward
5. MERCURY seems to initially come out in massive amount and than significantly decreases

THIS REQUIRES A BIT OF DISCUSSION AND OBSERVATION

The whole argument on the use of Calcium EDTA is Threefold
     1. It can be run in quickly in as short a time as a two minute push or the 30 minute plan
Used herein.
     2. It runs in relatively painlessly as compared to the older Magnesium EDTA (which used
To take 3 hours to infuse.)
     3. It Chelates both Mercury and the other Metals (Which is Optimized by the
Homotoxicology Protocol) without the need for other Chelators such as DMPS/DMSA

Looking at point number three regarding Mercury, we are reminded that the use of DMPS/DMSA sometimes causes a heavy metal Dump of significantly more Mercury than is achieved with this protocol. (The letters, e-mails and phone calls have been significant in this regard)

The one point that has been overlooked is that the Natural pathway of Mercury Elimination from the body is via the GI Tract and it is reasonable to expect that an IV Chelation method might also stimulate that pathway as opposed to the Kidney/Urine pathway.

WE HAVE BEEN REMISS in not also measuring fecal Mercury levels to see if this is where the Mercury is going in high amounts AND TO ALSO add the Homotoxicology Remedy MERCURIOUS HEEL to the Homotoxicology protocol. It is interesting to note the MERCURIOUS HEEL is a remedy that is indicated for infectious problems in the colon and its mechanism just might be that eliminating Mercury from the colon that the Terrain is restored to a meaningful level not allowing germs to remain in their virulent phases therefore further indicating that it CAUSES MERCURY to be eliminated down the GI TRACT. The Mercury Dumping with the Ca EDTA Chelation might be massive amounts BUT TO PROVE THIS we will need to collect stool samples from willing patients.

It is worth further pointing out that the New England Journal of Medicine in its Jan 23rd 2003 issue published a completed study Proving that Calcium EDTA Chelation does in fact improve Renal Function while its removing Lead from the system.

One can only imagine what would have been the case had they used the Homotoxicology protocols but a reading of that article will show that they based their numbers on 24 hour Urine Collections with only one gram infusions of the Ca EDTA but seemingly excreted less Lead than our group excreted and while its hard to correlate their statistics to ours seemed to this observer. To show that Homotoxicology increases at the very least the Lead excretion and therefore by extrapolation the other metals as well. (Realizing that we need to do a lot more studying to prove that assumption BUT WE CAN ADOPT THEIR MODEL FOR FUTURE STUDIES, as it was seemingly acceptable a method to the prestigious NEJM.)

With Ca EDTA having such a positive effect on metal elimination and also having such a positive effect as improving renal function it will pay for us to continue getting these needed answers to our questions using a model Chelator that both seems to work and is acceptable
As a safe product without untoward major side effects.

We clearly have our future work cut out for us but can clearly report improved subjective Patient satisfaction with decreased patient Circulatory Complaints and improvement in Longevity Findings as we are using this unique modality of Calcium EDTA and Homotoxicology. These need to be codified and reported in a future article as well.

@Copyright 2003 by Bruce H Shelton M.D.M.D.(h) DiHOM & HEEL Inc USA Medical Director