Added March 24, 2000

SUGGESTED   TREATMENT   PROTOCOLS
FOR  CFS / FM  PATIENTS 1


Heparin Time Line:
      |__________|__________|__________|__________|__________|__________|
Day 1               30 Days            60 Days           90 Days          120 Days         150 Days          180 Days

Transfer Factor Time Line:
                             |__________|__________|__________| 
                        30 Days            60 Days           90 Days          120 Days 
Antibiotics Time Line:
                             |__________|__________| 
                        30 Days            60 Days           90 Days 
Bromelain Time Line:For patients that have high Lp(a) or high PAI-1 values (500-1000mg/day). 
       |__________|__________|__________|__________|
 Day 1               30 Days            60 Days           90 Days          120 Days


 

Heparin Protocol:
See instruction sheet of Dr. Couvaras. (This sheet is not available online.  Conact David Berg at 800-999-2568 or by email for more information about this sheet). 
For a 150# slender patient, use 4000units, sq, BID.  If insurance will pay for LMWH (Lovenox), use 30 mg. in AM.
For a >150 # overweight patient, use 5000 units, sq, BID.  If insurance will pay for LMWH (Lovenox), use 30 mg. in the morning and 15 mg. at night.
It is suggested that heparin be continued for a time period after discontinuation of other therapies in order to prevent any remaining pathogens from activating the coagulation mechanism and starting the fibrin deposition cycle again.

Transfer Factor:
Transfer Factor (from colostrum) is available from several sources. The source that we have patient data using this protocol is Immunity Today, LLC (www.immunitytoday.com).  The dosage suggested by the company is 3 capsules per day. The cost is $270 for a 1 month supply. TF is more effective if started after heparin has been used for a period of time to allow some cleanup of fibrin deposition from endothelial cell surfaces in the capillaries.

Antibiotics:
Antibiotics, such as Doxycyline, may be used if there are known pathogens such as Mycoplasma or Chlamydia pneumonia. Each clinician must make the decision to use or not to use antibiotics based on their knowledge of their patient.

Bromelain:
 Bromelain may be used as an activator of fibrinolysis, especially in patients that have high Lp(a) or high PAI-1 values (which blocks fibrinolysis). A possible dosage is 500 to 1000 mg/day. There is no data that states that bromelain helps in these patients, but several journal articles suggest that bromelain does enhance fibrinolysis. Since bromelain is a natural substance from pineapples, it is an alternative to using tPA or Urokinase as fibrinolysis activators in patients.

1.     This protocol should be used only  under direction and supervision of the patient's physician. This suggested protocol has been developed by an Infectious Disease specialist and HEMEX Laboratories, Inc.  In no way should a patient treat him/herself.  HEMEX is in no way responsible for patient care. All drug precautions should be noted and followed. Questions can be addressed to  dberg@hemex.com.



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